Circulation on the Run

This week, please join authors Amil Shah and our own Peder Myhre, as well as Guest Editor Allan Jaffe as they discuss the article "NT-proBNP and Cardiac Troponin I, But Not Cardiac Troponin T, Are Associated with 7-Year Changes in Cardiac Structure and Function in Older Adults: The Atherosclerosis Risk in Community (ARIC) Study."

This week, please join author Robert Shaddy and Senior Associate Editor Victoria Delgado as they discuss the article "Sacubitril/Valsartan in Pediatric Heart Failure (PANORAMA-HF): A Randomized, Multicenter, Double-blind Trial."

This week, please join author Gilles Montalescot, Editorialist John Carroll, and Associate Editor Dharam Kumbhani as they discuss the article "Flecainide to Prevent Atrial Arrhythmia after Patent Foramen Ovale Closure, the AFLOAT Study: A Randomized Clinical Trial" and the Editorial "Atrial Arrhythmias After PFO Device Closure: Common, Clinically Important, and Preventable?".

This week, please join author Nigopan Gopalasingam, Editorialist B. Daan Westenbrink, and Associate Editor Justin Ezekowitz as they discuss the article "A Randomized Crossover Trial of Two-week Ketone Ester Treatment in Patients with Type 2 Diabetes and Heart Failure with Preserved Ejection Fraction" and the editorial "Ketone Treatment in Heart Failure with preserved Ejection Fraction: Recharging the Heart or Reducing Filling Pressures?".

This week, please join author Kashish Goel and Associate Editor Dharam Kumbhani as they discuss the article "Contemporary Outcomes and Trends for the Transseptal Mitral Valve-in-Valve Procedure Using Balloon Expandable Transcatheter Valves in the United States."

This week, please join authors Regina Royan and Tracy Madsen as well as Associate Editor Deborah Diercks as they discuss the article "Disparities in EMS Use, Prehospital Notification, and Symptom Onset to Arrival in Patients with Acute Stroke."

This week, join Associate Editor Marc Ruel who briefly summarizes Circulation's annual Surgery Issue. Then he is joined by author André Lamy and they discuss the article "Topical Versus Intravenous Tranexamic Acid in Patients Undergoing Cardiac Surgery: The DEPOSITION Randomized Controlled Trial." Then Marc is joined by author Niccolò Maurizi and they discuss the article "Long-term Outcomes after Septal Reduction Therapies in Obstructive Hypertrophic Cardiomyopathy: Insights from the SHARE Registry."

This week, please join authors Shaan Khurshid and Shinwan Kany as they discuss the article "Associations of “Weekend Warrior” Physical Activity with Incident Disease and Cardiometabolic Health."

This week, please join author Luigi Di Biase as he discusses the article "Pulsed Field Ablation to Treat Paroxysmal Atrial Fibrillation: Safety and Effectiveness in the admIRE Pivotal Trial."

This week, please join authors Marcelo Di Carli and Jenifer Brown, as well as Associate Editor Vlad Zaha as they discuss the article "Relationship of Subendocardial Perfusion to Myocardial Injury, Cardiac Structure, and Clinical Outcomes among Patients with Hypertension."

This week, please join author Chen Chen and Associate Editor Sergio Lavandero as they discuss the article "LncRNA DCRT Protects Against Dilated Cardiomyopathy by Preventing NDUFS2 Alternative Splicing via Binding to PTBP1."

This week, please join a panel session with authors Timothy Poterucha and David Ouyang, Editorialist Anna Sannino, and Senior Associate Editor Victoria Delgado as they discuss the Original Research Articles "Deep Learning for Echo Analysis, Tracking, and Evaluation of Mitral Regurgitation (DELINEATE-MR)" and "High Throughput Deep Learning Detection of Mitral Regurgitation."

This week, please join author Bruce Wasserman and Associate Editor Mercedes Carnethon as they discuss the article "Intracranial Atherosclerotic Disease and Incident Dementia: the Atherosclerosis Risk in Communities (ARIC) Study."

This week, please join author Gregory Wyant and Associate Editor Gabriele Schiattarella as they discuss the article "Induction of DEPP1 by HIF Mediates Multiple Hallmarks of Ischemic Cardiomyopathy."

This week, please join author Gary Owens and Associate Editor Iris Jaffe as they discuss the article "A Novel Mouse Model of Myocardial Infarction, Plaque Rupture and Stroke Shows Improved Survival with Myeloperoxidase Inhibition."

This week, please join author Marius Hoeper and Associate Editor Kelly Chin as they discuss the article "Tadalafil for Treatment of Combined Post- and Pre-capillary Pulmonary Hypertension in Patients with Heart Failure and Preserved Ejection Fraction: A Randomized, Controlled Phase 3 Study."

This week, please join author Rachel Lampert and Guest Editor Arthur Wilde as they discuss the article "Vigorous Exercise in Patients with the Congenital Long QT Syndrome: Results of the Prospective, Observational, Multinational, “Lifestyle and Exercise in LQTS” (LIVE-LQTS) Study."

This week, please join author Hiroyuki Daida and Associate Editor Amit Khera as they discuss the article "A Randomized Trial for Evaluation in Secondary Prevention Efficacy of Combination Therapy - Statin and Eicosapentaenoic Acid (RESPECT-EPA)."

This week, please join author Rod Passman and Associate Editor Mark Link as they discuss the article "Association of Atrial Fibrillation Burden and Mortality Among Patients with Cardiac Implantable Electronic Devices."

This week, please join author John JV McMurray and Guest Editor Frank Ruschitzka as they discuss the article "Effect of Sacubitril/Valsartan on Cognitive Function in Patients with HFpEF: A Prespecified Analysis of PARAGON-HF."